This video presents a visualisation of the current prototype packaging concept for the XENO:K delivery mechanism, as we envision it following final testing and validation.
XENO:K is designed to offer several potential advantages for surgeons performing tendon and ligament reconstruction procedures:
High Native Strength: Kangaroo tendons are known for their high tensile strength—up to 6X that of human tendon in their native state—providing a strong biologic starting material for graft development.
Scaffold for Cellular Infiltration: The decellularized extracellular matrix is intended to serve as a functional scaffold that supports host cell infiltration and tissue integration over time.
No Autograft Harvesting Required: As an off-the-shelf option, XENO:K is designed to eliminate the need for harvesting the patient’s own tissue, potentially simplifying the procedure and avoiding donor site morbidity.
Allograft Alternative: XENO:K offers an alternative to cadaveric allografts, which may have limitations such as availability, preparation time, or disease screening/ sanitization considerations.
Reliable Supply Chain: Sourced through regulated wild game meat suppliers, kangaroo tendon provides a traceable and scalable supply of high-quality raw material.
Consistent Quality and Biocompatibility: Kangaroo-derived grafts are manufactured in accordance with ISO 13485 standards to ensure consistency and are sourced from tissue with inherently low risk of transmissible spongiform encephalopathies (TSEs).. The use of kangaroo tissue may also present fewer cultural or religious concerns compared to bovine or porcine materials.
Ginan Biomedics
Repair Implant
A biological scaffold intended to support the repair of tendon injuries by providing a structural environment conducive to soft tissue regeneration and repair quality. Designed as a sterile, readily available device for use alongside existing surgical techniques for tendon repair.
Ginan Biomedics
Reconstruction Implant
An advanced biological scaffold with viscoelastic and biomechanical properties that mimic load bearing dense connective tissue. The device is intended to be implanted during tendon or ligament reconstruction to provide full biomechanical stabilisation during the healing process, offering a biological alternative to allograft and autograft options. Designed as a sterile, readily available device of known sizes for ease of graft assembly.
Early indications from surgeons
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I have been researching ACL outcomes in my academic career for many years. Up until now, I have not found the ideal graft that meets all our requirements. However, in my analysis of data provided by Dr Hartnell and his team, Xeno:K preliminary data is potentially the break-through the world has been looking for.
A/Prof Samuel J. MacDessi MBBS(Hons)FRACS FAOrthA
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Using a kangaroo tendon xenograft as an alternate graft choice is a novel biological technique in ACL reconstructive surgery which has great promise.
Dr Darren B. Chen MBBS(Hons)FRACS FAOrthA
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The Xeno:K Project is looking at the viability of a biological xenograft to be used as an ACL reconstruction graft which has strength and biology, is available and affordable, and avoids donor site morbidity. I fully support the ongoing research in this field, and I hope to use it in my patients as I see a real deficiency in the market which could be filled by use of xenograft. I am encouraged and excited by the early data from the Xeno:K project.
A/Prof Justin P. Roe MBBS.BSc.(Med) FAOrthA